Description

Hypothermia is a well know protection principle for the storage and transport of cells. It slows down cell metabolism and reduces damaging processes caused by lack of oxygen or substrate. Something like when animals hibernate. Unfortunately this cold can cause damage to the stored cells and that is where ROKEPIE comes in. With adding ROKEPIE to cells and tissues they are prevented from such damages which will lead to significant longer period of cold storage. Can you imagine what this can mean for you? An extension of the transportation time which is ideal for international destinations but also a longer storage time so you can pause the cells during production or development activities. It also supports cell growth upon rewarming at 37°C which makes ROKEPIE the first choice for researchers, physicians and scientist all over the world. And did we mention the 3 year shelf-life of our formulation? ROKEPIE will be delivered in freeze-dried formulation and can be stored for approx. 3 years.

Product details
– ROKEPIE will be delivered as a freeze-dried (lyophilized) formulation
– The lyophilized ROKEPIE formulation is sufficient for 2ml stock solution
– The 2ml stock solution can be used to make 50 to 200ml of hypothermic storage cell culture medium, depending on cell density and cell line in question
– Dissolve the lyophilized ROKEPIE, add to cell culture, incubate and use
– Small molecule (MW ≈ 400)
– Sterile additive
– Pyrogen free
– Contains a single well-defined component
– Non-toxic conform ISO-10993-5:2009
– Fully synthetic, no animal components
– Free of antibiotics & preservatives
– Non-toxic, there is no need for replacing storage solution after rewarming up to 37°C
– Growth is directly supported after reaching 37°C
– Tested in HEK293, CaCo-2, SMAC, SKOV and human blood cells
– ROKEPIE®-FD01 has shown no plastic-binding properties
– For Research Use Only – RUO
– Patent pending
– The shelf-life of lyophilized ROKEPIE is 3 years